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The cost-effectiveness calculation must consider not just price but also efficacy likelihood and safety profile for each delivery method

Accelerating approval of these next-gen formulations by ten to eleven months doesnt change the patent timeline, but it compresses the product cycle: a higher-dose Wegovy and an oral Foundayo reach physicians and patients sooner, generate revenue sooner, establish market position sooner, and create clinical inertia patient stabilization on a specific formulation that makes future price negotiation more difficult for any payer, including CMS

The mechanism involves the sudden spike in growth hormone affecting various systems simultaneously

Analysis of data from randomised trials disproved that theory