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Apnimed anticipates submitting AD109 for FDA review in 2H2025
Mechanism in research literature NNMT (nicotinamide N-methyltransferase) catalyses the methylation of nicotinamide using S-adenosylmethionine (SAM) as the methyl donor, producing 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine
69 Proteins, including PCNA, XPC, DDB2, RRM2B, PIG3 and POLH, are activated to promote DNA repair
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