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The concern lies not with the medication itself acting directly on bone though some emerging data is beginning to explore GIP receptor activity on osteoblasts but rather with the metabolic consequences of the substantial weight loss that Mounjaro produces

Type 2 Diabetes Management: People with type 2 diabetes have difficulty controlling their blood sugar levels because their bodies do not use insulin properly

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The addition of a glucagon receptor component may theoretically affect reflux differently, but comparative data is still limited