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This is important because some individuals, especially those with specific health conditions (like genetic mutations or absorption issues), may have difficulty metabolizing regular B12
Transcellular transport requires specific mechanisms (receptor-mediated transcytosis, active transporters) which may not exist for all peptides
This means people following restricted diets may be more likely to develop low levels over time
There, they break apart and are absorbed by the lining of the rectum, which is a good avenue for absorbing various molecules
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