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Notably, no sign of hepatotoxicity was reported when 4 g/d APAP was administered for up to 12 months to adult patients with osteoarthritis pain ( Reference Temple, Benson and Zinsenheim 91 )

Onofrj M, Fulgente T, Melchionda D, et al

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Safety and Efficacy: Although some studies have indicated that glutathione can improve skin tone and reduce hyperpigmentation, the need for well-designed, large-scale studies remains