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Most side effects are temporary when the medication is started at the lowest dose and slowly increases over time

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In a landmark phase II study, semaglutide demonstrated NASH resolution without worsening of fibrosis in 36 to 59% of patients with liver fibrosis, compared with only 17% in the placebo group

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The FDA has added warnings to GLP-1 drug labels, including Trulicity and Ozempic, regarding gastrointestinal complications

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