Osteocalcin and its endocrine functions
The study also indicated that GLP-1 RA treatment was associated with a moderately increased risk of gallstones (RR: 1.27, 95% CI 1.101.47), cholecystitis (RR: 1.36, 95% CI 1.141.62), and overall gallbladder disease risk (RR: 1.55, 95% CI 1.082.22) compared to placebo
Thats been, like, another big, concerning thing among clinicians cause when you think about weight loss, whether its through a GLP-1 drug, exercise, diet or something like malnutrition, youre losing all different, quote, unquote, types of weight
The trial was preregistered at ClinicalTrials.gov (NCT06309667) on February 14, 2024, and conducted in accordance with the Declaration of Helsinki and the International Council for Harmonisation Good Clinical Practice guidelines