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In subunit 2 the domain I helices are dark cyan -strands are orange, and the domain II helices are light cyan
That means that a big open question is whether the side effect profiles may differ in subgroups of people that scientists have not directly studied, which include a large swath of people now taking these drugs to lose only about 10 to 15 pounds
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Key findings: STEP 1 (68 weeks, 2.4 mg Wegovy, n=1,961): 44% of participants reported nausea, with the majority resolving it within the dose-escalation phase
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