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GLP-1-class drugs amplify this in one indirect way: they work largely by suppressing appetite, which can drive protein intake and overall calories very low if a person simply "isn't hungry." Under-eating protein while losing weight quickly is the single biggest driver of avoidable muscle loss
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If affordability or insurance coverage for weight loss is an issue, you may qualify for a GLP-1 with another condition such as obstructive sleep apnea or type 2 diabetes, says Moreno
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