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Pharmaceuticals (Basel) 17:267 Li X, Luo R, Chen R, Song L, Zhang S, Hua W, Chen H (2014) Cleavage of IB by calpain induces myocardial NF-B activation, TNF- expression, and cardiac dysfunction in septic mice

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Switching injection sites, adjusting injection timing relative to meals, or adding anti-nausea medication during the adjustment period are all standard interventions with clinical support

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