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These findings suggest that part of the clinical benefit of GLP-1RAs in PsO may derive not only from metabolic improvements but also from direct modulation of adipose-driven inflammatory pathways

Ten animals were allocated into two groups of five: a HAART-treated group (Group A) administered 1.88 mg of the drug combination dissolved in 0.1 ml of normal saline, and a control group (Group B) receiving equivalent volume of normal saline as placebo

In February 2025, Gan & Lee Pharmaceuticals (hereafter referred to as "Gan & Lee," stock code: 603087.SH) unveiled that the first participant was successfully dosed in a large-scale Phase 3 clinical trial (OPTIMUM-2) of Bofanglutide, a bi-weekly glucagon-like peptide-1 receptor agonist (GLP-1RA) independently, in Chinese participant with type 2 diabetes mellitus (T2DM)

The BDF-L group showed no significant changes