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PBMs often change drug coverage based on rebates, not what's best for disease management, disrupting care and driving up short and long-term costs
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This effect is dose-dependent and may diminish with continued use Central appetite regulation : They act on receptors in the hypothalamus and other brain regions to reduce appetite and food intake Most GLP-1 agonists are administered via subcutaneous injection, with dosing frequencies ranging from once daily to once weekly depending on the specific agent
