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However, our findings are consistent with previous studies of other BBSome genetic knockouts ( Bbs2 / and Bbs4 / ), which demonstrate that dysregulated leptin receptor signaling is a key ciliopathy-mediated disruption contributing to obesity in BBS

Ferroptosis is an iron-dependent form of regulated cell death, closely associated with disruptions in iron homeostasis, dysfunction of amino acid antioxidant systems, and lipid peroxidation (Jiang et al., 2021

The goal is to help you eat enough protein, fiber, and overall nutrition, not to create another restrictive diet