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This study aims to address these gaps through an extensive review of clinical trials with network meta-analysis, complemented by a systematic review of preclinical studies with SGLT2is and GLP-1 RAs

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Repeated measures analyses of weight, waist and BP At years 1 and 2, the repeated measures analyses, performed in support of the primary ANCOVA analyses, in general gave slightly greater estimates for weight and waist change, slightly lower estimates for systolic BP and similar estimates for diastolic BP (Supplementary Tables 3 and 4)

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