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E., & Rutkove, S
Inactivation of GA3PDH is important because of its potential to increase the production of a side-product, methylglyoxal, and redirect glycolytic intermediates to the biosynthesis of lipids
Studies using adult human peripheral T cells demonstrated that glutamate at low concentrations ( 1 mM), however, this effect reversed, indicating that glutamate tends to have immunosuppressive properties at higher concentrations (176, 178)
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