The most important serious side effects include acute pancreatitis (severe persistent abdominal pain radiating to the back, though clinical trials found similar pancreatitis rates to comparators), severe dehydration from persistent vomiting or diarrhea (signs include dizziness, decreased urination, extreme thirst), gallbladder disease including cholecystitis or cholelithiasis (right upper quadrant pain, fever, jaundice), severe allergic reactions (difficulty breathing, swelling of face or throat), and severe hypoglycemia when combined with insulin or sulfonylureas (confusion, loss of consciousness, seizures)
(1986) Wilson's disease: clinical presentation and use of prognostic index
Studies suggest that precursor support can improve glutathione status in selected populations, but responses vary and broader anti-aging claims remain unproven
A: Glutathione Effervescent Tablets have a shelf life of 18 months from manufacturing