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For patients without absorption disorders, high-dose oral supplements of 1,000 to 2,000 mcg daily have been shown to be comparably effective at correcting mild to moderate deficiency at lower cost and greater convenience.
For instance, because of its role in DNA repair, it is essential for cell division and plays a significant role in the formation and repair of all cells
It's about whether your study design requires stable, predictable plasma curves or whether you're willing to accept 1525% variability in absorption depending on anatomical factors outside your control
Always check with a pharmacist first
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