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Given that infusions of GLP-1(2836) and GLP-1 have been shown to influence body weight and blood glucose levels in high-fat dietfed mice (24) and that we ourselves have documented an effect of calorie restriction and weight loss on cardioprotection (25), we examined the consequence of our 14-day infusions on these parameters

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Recent clinical evidence reinforces this integrative framework by showing that GLP-1RA and dual incretin agonists modify taste-related behavior through coordinated gastrointestinal, hormonal, and central mechanisms