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Limitations: What the Research Does Not Establish A responsible reference article is defined as much by what it refuses to claim as by what it asserts

This detoxifying effect can indirectly contribute to healthier skin by reducing the burden of toxins that may lead to skin issues such as acne or inflammation

Factors such as trauma, nutritional deficiencies, irritable bowel disorders, leaky gut, microbiome dysbiosis, and immune dysregulation can all contribute to the generation of ROS, leading to tissue damage and ulcer formation

Mitochondrial proteomic datasets reveal that adipose depots have distinct respiratory chain compositions and CI regulatory inputs, further supporting the idea that reduced CI function differentially affects distinct adipose tissue depots 52,53