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A lipidation moiety enables albumin binding and a prolonged duration of action in experimental research models
it also improved oral glucose tolerance and reduced gastric emptying
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Clinical trials of Wegovy have shown that it is most effective when used in conjunction with intensive lifestyle interventions (ILI), including a healthy, balanced diet and increased physical activity
Although the reasons for the variation are still unclear, this might be due to several differences in the individual study design and patient characteristics rather than drug effect [21]
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