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In a controlled clinical trial, 70% of women showed improved skin collagen after thigh treatment compared to 50% with vitamin C and 40% with retinoic acid
The researchers reported significant improvement during one month of glutathione treatment
Complete pharmacokinetic studies and long-term evaluations are rare
(PubMed) The same review warns that systemic administration (IV) may shift melanin production, altering skins natural photoprotection and potentially increasing the risk of UV-induced skin damage or cancer a risk especially relevant in sunny climates
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