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The study "Liraglutide versus placebo as an adjunct to glucose-lowering therapy in patients with type 2 diabetes and moderate renal failure" (LIRA-RENAL) did not demonstrate a benefit of liraglutide in lowering eGFR, although the duration of the study (26 weeks) may have been insufficient to show an effect

Additionally, the mean age of participants in the semaglutide study (63 years) was significantly higher than in the liraglutide study (46 years) and had a higher peak age of 85 compared to 65

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