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Likewise, for assessing the change in relative IBA1 or GFAP in the hippocampus or entire brain following semaglutide treatment, a linear model was constructed for each protein and each brain region using the protein percentage as dependent variable and treatment (veh-LPS and sema-LPS) and time (2d and 11d after the last LPS injection) as independent variables with interaction effects

Liu T, Zhong S, Liao X, Chen J, He T, Lai S, et al

Conclusion Understanding the roles of PYY and GLP-1 in regulating appetite and metabolism provides valuable insights into managing weight and improving overall health

We prioritized designed sequences with the smallest (first generation) and largest (third generation) distance from the training set