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1995, 26 (Suppl 1): 137-141
In recent years, a new class of drugs has gained significant attention in the medical world, promising substantial weight loss and potential changes in healthcare costs
The conflicting data in some clinical studies may be explained by various factors: [1] most cohort studies lacked individual validation of fractures as primary outcomes, [2] the studies had short follow-up duration and [3] did not consider important risk factors for osteoporosis such as BMD (even though BMD is not a good method for diagnosing osteoporosis in T2DM), and [4] some studies included medications that affect fracture risk, such as corticosteroids or antidepressants
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