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A second study investigated delivery of GLP-1 in a SOD1 G93A mouse model using an intracerebroventricular injection of mesenchymal stem cells (MSC) stably transfected to secrete GLP-1 21
There are conflicting results possibly due to differences in experimental design
These drugs by increasing insulin secretion and possibly, beta cell mass, decrease plasma glucose and lipids and have a secondary action to reduce food intake and bring about weight loss
Its stable, resists breakdown in the digestive tract, and can reach the bodys cells intact
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