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This was observed in genetic models of hypertension, such as aged spontaneously hypertensive rats, 111, 112 stroke-prone spontaneously hypertensive rats, 113 Type 2 diabetic, mildly hypertensive GotoKakizaki rats 114 and TGR(mREN2)27 renin transgenic rats, 115 as well as in several models of drug-induced hypertension

1 Given the supply challenges and cost of these drugs, additional information about patient demographics, prescribing patterns and the magnitude of on- vs

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However, this event was associated with the concurrent use of ondansetron (an anti-nausea medication), not directly attributable to retatrutide itself