Citicoline was found to enhance retinal function and neural conduction along post-retinal visual pathways, such that responses of the visual cortex to stimuli were significantly improved compared to placebo (87)
The H-ESI source was operated in positive mode at spray voltage 3,500 or negative mode at spray voltage 2,500 with the following parameters: sheath gas 35 a.u., aux gas 7 a.u., sweep gas 0 a.u., ion transfer tube temperature 320 C, vaporizer temperature 275 C, mass range 70 to 1,000 m/z , full scan MS1 mass resolution of 120,000 FWHM, RF lens at 70% and standard AGC
The transcriptional activation of genes encoding other enzymes of the PPP also occurs in response to oxidative stress and the demands of increased anabolic metabolism
10.1002/bdd.593 80 PistrittoG.TrisciuoglioD.CeciC.GarufiA.D'OraziG