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The deprotection of Lys protected with Dde or ivDde protecting groups requires the use of a hydrazine solution, which has a strong reductibility, and easily undergoes a side reaction with an oxidizing group

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The most frequently reported side effects in Phase 2 trials are gastrointestinal: nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

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We conducted a subgroup analysis based on age to assess the proportional imbalance of AEs related to suicide/self-injury for GLP-1RA within different age groups

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