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GHK naturally occurs in human plasma at approximately 200 ng/mL in young adults, declining significantly with age (PMID 29986520)
Elevated levels of ferritin and transferrin, markers of iron dysregulation, have been observed in clinical ARDS cases, linking iron metabolism to disease severity ( Mitochondrial dysfunction exacerbates iron-driven ferroptosis by impairing the organelles ability to sequester and regulate iron levels
Shug A et al
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