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It is interesting to note that other post-acute infection syndromes (PAIS) and some neuropsychiatric diseases such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), depression (especially the atypical/immunometabolic subtype (IMD) [86]) and others also have fatigue as a leading clinical symptom, which may serve as a model for investigating the mechanisms of fatigue and drawing conclusions regarding therapeutic options in long COVID
Immune senescence is an important risk factor for pneumonia, and, therefore, natural compounds shown to combat immune senescence may help reduce pneumonia risk
2006 Apr;27(4):921-30
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