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Cardiac disease, pulmonary disease, active psychiatric instability, or any history that makes decompensation more likely should move the conversation away from casual home detox and toward monitored care

(FDA oversight is basically an established safety standard regarding how a product is manufactured in a compounding pharmacy facility, less so about its performance or safety.) A reversal would not automatically open the floodgates, but it would be a significant change, notes Hajduczok

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