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The theoretical advantage of adding glucagon activity is greater energy expenditure and liver-fat reduction
Therefore, only ACC1 isoform is expressed in tumor cells under acidosis to produce malonyl-CoA as a substrate for FA synthesis
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doi: 10.1371/journal.pone.0127558 49 KubotaMNakataRAdachiSWatanabeKHeikeTTakeshitaYet al
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