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Muscle mass preservation is an important consideration given the risk of sarcopenic obesity: weight loss with GLP-1 RAs includes a lean mass component (approximately 25%-40% of total weight loss), though the clinical significance in MASLD patients without sarcopenia is uncertain
Restaurant chains are also making changes
Plateaued on Semaglutide: If youve been taking semaglutide and hit a plateau, switching to tirzepatide often produces additional weight loss
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