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AHK-Cu is structurally related to other copper peptide systems, but differs by its alanine-histidine-lysine sequence, which may contribute to distinct receptor interactions and experimental behavior compared with glycine-based copper tripeptides

While disorders affecting the lower motor neurons, such as ALS, post-polio syndrome, spinal muscular atrophy (SMA), or progressive muscular atrophy, can cause twitches, they almost never appear alone

We suggest that this highlights the importance of proactive integrated physical and mental healthcare for all those suffering with HG, regardless of physiological severity