Baric I, Zschocke J, Christensen E, Duran M, Goodman SI, Leonard JV, Muller E, Morton DH, Superti-Furga A, Hoffmann GF: Diagnosis and management of glutaric aciduria type I
Call 999 or go to your nearest A&E immediately if you experience: Signs of a serious allergic reaction (anaphylaxis) , including facial or throat swelling, difficulty breathing, a rapid heartbeat, or a widespread rash this is a medical emergency Severe difficulty breathing or collapse Contact your GP, NHS 111, or your trial medical team promptly if you experience: Persistent or severe vomiting or diarrhoea that prevents adequate fluid or food intake
These are observational studies, so they examine correlation rather than causation
High glucose increases glomerular filtration barrier permeability by activating protein kinase G type I subunits in a Nox4-dependent manner