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Not exactly they address different things
Suspensions were centrifuged at 5,000 g for 5 min at 4C, supernatants were transferred to a new tube, and TCA buffer was added to a final concentration of 33% and incubated at 4C overnight to precipitate histone proteins
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All these observations were confirmed and supported by in vitro experimental data, including evaluation of cytotoxic effects on healthy RBCs [269,270,271]
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