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Mood improvements may result from better glycaemic control, weight loss, improved physical health, and enhanced self-esteem rather than direct effects on serotonin or other mood-regulating neurotransmitters
Beyond glycemia: Comparing tirzepatide to GLP-1 analogues
*Based on self-reported member data on a Found program from members with no prior weight loss medication use, who reported weight loss of 12.1% in 6 months on compounded tirzepatide, as of April 2026
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