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Last but not least, their favorable cardiovascular (CV) properties in blood pressure, endothelial function and myocardial metabolism 2,3 exemplified in the LEADER trial 4 and other studies, 5 in which a significantly lower risk of CVD events was demonstrated with liraglutide in patients with T2DM, are of major clinical importance when considering the increased risk of CV and all-cause mortality in patients with T2DM

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Even though most of these drugs do not cross the blood-brain barrier, brain fog is often one of the first symptoms affected and may be due to improvements in blood flows

Integration of the metabolic and bioreactor levels